At present, modern medicine has established a comprehensive and systematic treatment system for vitiligo. The specific treatment plan must be comprehensively determined by doctors based on factors such as the location of white patches, lesion area, patient’s age, skin type and disease stage, and either monotherapy or

At present, modern medicine has established a comprehensive and systematic treatment system for vitiligo. The specific treatment plan must be comprehensively determined by doctors based on factors such as the location of white patches, lesion area, patient’s age, skin type and disease stage, and either monotherapy or combination therapy will be selected. Common treatment methods are as follows:

1.Topical Medication Treatment

Commonly used clinical drugs include glucocorticoid ointments (e.g., mometasone furoate cream), calcineurin inhibitors (e.g., tacrolimus ointment), and vitamin D3 derivatives (e.g., calcipotriol ointment). In addition, small-molecule JAK inhibitors (e.g., topical application of 1.5% ruxolitinib cream) have also shown certain curative effects, but they have not yet been approved for clinical use in China.

2.Phototherapy Technology – Activating Pigment Regeneration

It activates melanocyte regeneration through specific wavelengths of light, including 308nm excimer laser (suitable for precise treatment of localized white patches), narrowband UVB phototherapy (NB-UVB, applicable to systemic or local use, for non-segmental or mixed vitiligo with scattered or extensive lesions), and home phototherapy (suitable for localized white patches in easily accessible areas).

3.Systemic Treatment

Its core is to regulate the disordered immune system. For patients in the rapidly progressive stage, low-dose oral hormones, immunomodulators and other drugs can be administered under the guidance of doctors to block disease progression.

4.Surgical Transplantation Treatment

It is only applicable to localized white patches in the stable stage (no new white patches and no enlargement of existing ones for at least 6–12 months) with poor response to medication and phototherapy, such as autologous epidermal transplantation. It is not the preferred treatment option for early-stage vitiligo.

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